PharmD Consult - The Magic Mushroom Interaction Checker
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For Centers, Facilitators, Guides, Providers & Participants​ ​

Providers, Facilitators/Guides, Centers: Support safe access by reducing unnecessary disqualifications and ensuring decisions are informed by accurate pharmacologic understanding

Check the full medication mix with psilocybin, not just individually with psilocybin (a major advantage over the Interaction Checker tool)​

Reduce preparation anxiety and guesswork ​

Get professional guidance specific to your case

Receive professional documentation​

Reduce risk and potential harm​

In a world where answers are easy to find but harder to trust, rely on professional, personalized, evidence-informed guidance

Dr. Kristin Speer, PharmD​

Board-certified pharmacotherapy specialist and licensed pharmacist with extensive experience in clinical practice, psychedelic interactions, and personalized medication management. Dedicated to ensuring safety, preventing avoidable setbacks that can erode hope, and supporting better outcomes through evidence-informed guidance.​

My Story

 

On April 20th, 1999, I sat in lock-down at Chatfield Senior High while the Columbine massacre unfolded nearby at our rival high school. From the floor, my classmates and I watched the horror play out on the television, powerless as the tragedy unfolded in real time. (Ironically or not, this happened during my Humanities class.)  For the remainder of the school year, displaced Columbine Rebels finished their school year in our classrooms. In that moment, the rivalry between our schools disappeared and we became one community. Those shared months taught me more about the human capacity for devastation, grief, and resilience more profound than anything I’d find in any curriculum. One moment I’ll never forget was hugging a Columbine friend whom I didn’t know had just undergone surgery to remove shrapnel from her chest. What should have been a gesture of comfort caused her pain, not from sorrow or relief, but from the raw wounds still healing beneath her bandages. That experience, the collision of trauma, vulnerability, and the desperate need for healing, left a lasting imprint on me. At such a formative time in my life, it shaped my path and instilled in me a commitment to mental health, spiritual health, trauma recovery, and safe access to care.

 

That commitment continues to guide my work today. I became a pharmacist because I wanted to bring science, safety, and compassion into some of the most difficult moments people face: pain, serious illness, mental health struggles, and end-of-life transitions. Over the years, I’ve practiced and consulted in hospice and palliative care, pain management, psychedelic and natural medicines, and prescription drug benefits. In every role, one thread has remained constant: my focus on pharmacologic safety and effectiveness—ensuring patients living with complex medication regimens and medical conditions are supported with clarity, autonomy and dignity.

 

My work now bridges clinical practice, consulting, policy, and harm reduction, with a focus on psychedelic therapies. I co-founded the Psychedelic Pharmacists Association to elevate pharmacists as key partners in psychedelic care, and I’ve been honored to serve as a pharmacology expert for Colorado’s Department of Regulatory Agencies (DORA) and the Healing Advocacy Fund (HAF). Through this work, I co-developed the screening criteria that became the foundation for Colorado’s Natural Medicine Health Act. Those same criteria have since been adopted in Oregon’s program and are now integrated into screening and decision-support platforms used by regulated facilitators and clinics across the country.

 

Why did I create the Psilocybin Interaction Checker and begin offering consultations? Because trusted resources are limited for those navigating the intersection of psychedelics and medications. Psychedelics hold enormous promise, but they are not risk-free. Many individuals seeking these therapies are on complex medication regimens which have the potential to sabotage healing—despite skilled facilitation and integration support.  Without reliable, evidence-informed guidance, people are left guessing. That gap in care is what I set out to fill.

 

The Interaction Checker is one way I’ve done this: it’s a transparent, peer-reviewed tool designed for individuals, facilitators, and providers. My consulting services are another. Each consultation is rooted in pharmacologic and clinical evidence, tailored to the person, and designed to ensure safety while honoring autonomy and access. Whether it’s helping an individual prepare for a journey, or supporting a facilitator in meeting state screening requirements, my role is to provide clarity where there is confusion. And to build in safety where there is risk.

 

Along the way, my work has been recognized with honors such as Medika Life’s Top 30 Women Transforming Healthcare and the University of Colorado School of Pharmacy Horizon Alumni Award. But for me, the real measure of success is trust: the trust patients and participants place in me, the trust facilitators place in my assessments, and the trust of regulators who continue to turn to pharmacists as essential partners in this field.

 

This path began in tragedy, but it has carried me into a career defined by hope… a hope that psychedelic therapies, when integrated responsibly, can remain accessible and bring healing to individuals and communities who need it most.

 

 

Professional Summary

  • Residency-trained and board-certified pharmacist (PharmD, BCPS), licensed in Colorado
  • Co-founder & Board Director, Psychedelic Pharmacists Association
  • Pharmacology expert for Colorado’s Department of Regulatory Agencies (DORA) and the Healing Advocacy Fund (HAF)
  • Co-developer of screening criteria for Colorado’s Natural Medicine Health Act, later adopted by Oregon and integrated into facilitator/clinic decision-support platforms nationwide
  • Creator of the Psilocybin Mushroom Interaction Checker at psychedelicinteraction.com
  • 15+ years of experience across palliative and hospice practice, pain management, consulting and pharmacy benefits
  • Developed curriculum for nationally recognized PharmD program and the nation’s first Palliative Care Master’s degree program
  • Delivered nationally distinguished educational presentations and continuing education programs
  • Peer-reviewed researcher and published co-author in biomedical literature
  • Recognized among Medika Life’s Top 30 Women Transforming Healthcare (2022)
  • Recipient of the University of Colorado School of Pharmacy Horizon Alumni Award (2022)

Consulting Services

Pharmacologic Review Triage (PRT) Consult

Our most popular consult. Receive a personalized, high-level risk assessment documentation that screens current medications, over-the-counter (OTC) products, and substances for any contraindicated or high-risk interactions or concerns with a planned psilocybin journey. This is an on-paper review only; no live meeting is offered with this consultation. This screening may be helpful to determine if a deeper Comprehensive Review & Pharmacologic Management (CRPM) consult could be beneficial (aka “triage”); however, it is not necessary to get a CRPM.

See full description

Up to 5 meds​

$100​

Up to 10 meds​

$150​

Up to 20 meds

​$200​

Comprehensive Review and Pharmacologic Management (CRPM) Consult

Receive a complete pharmacologic evaluation and personalized medication management and safety plan in preparation for a psilocybin journey. For those who want careful guidance and more confidence. Includes a detailed written report plus a 30-minute live meeting. You may invite an attendee. Being on camera is not required.

See full description

Up to 5 meds​

$200​

Addn’l meds​

$15 each​

Informational Consult

This consult type is designed to provide pharmacology education and clinical insights about psilocybin, MDMA, ibogaine, ketamine and other prescription & over-the-counter (OTC) products. Get pharmacology education, general drug interaction (compatibility) checks, and general clinical insight related to plant medicines/psychedelics, medications and potential risks from a professional—not AI. No personalized intake required. Includes a written response and an optional 15-minute live review of the response(s). Being on camera is not required.

See full description

$150​

Pharmacologic & Drug Interaction Insights

Psychotropic Interactions are Just the Beginning

But Contraindications Don’t Have to Be the End.   Common misperception: “There aren’t many interactions with psilocybin—mainly antidepressants, lithium and antipsychotics.”   Unfortunately, this idea is not backed by evidence.   Nor the deep knowledge of pharmacists.   As psychedelic use grows—both through formal access programs and informal demand across populations—we need to broaden our […]

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AI vs Pharmacist Advice – Trazodone tapering example

  The growing reliance on AI-generated healthcare advice presents significant risks. While technology promises accessibility and convenience, it often delivers generalized, incomplete and over-confident guidance that can lead to suffering and treatment delays.     Two cases involving trazodone management illustrate the compelling difference between algorithmic recommendations and professional expertise: one participant experienced unnecessary withdrawal […]

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Why Oregon’s “Rare” Adverse Event Findings May be Missing the Full Picture

  When people point to Oregon Psilocybin Services (OPS) and say adverse events are “rare,” it can sound like psilocybin is virtually risk-free. But the truth is more complicated. The way adverse events have been defined, collected, and reported have potentially overlooked important outcomes that can affect a person’s healing journey.     Narrow Definitions […]

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Why Providers and Facilitators Rely on Pharmacists for Drug Interaction Expertise

  When considering psychedelic interactions, a common misperception arises: “Providers and facilitators already know all the relevant drug interactions—so why involve a pharmacist?”     Debunking the Idea That Providers and Facilitators Know All the Interactions   In reality, while providers have broad medical training and licensed facilitators may receive some instruction on interactions, neither […]

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What Colleagues and Clients are Saying​ ​

Dr. Speer’s professionalism, expertise, and commitment to raising the bar for screening standards is exceptional. I have felt so fortunate to collaborate with her on developing the medical and psychological screening tool for Colorado’s Natural Medicine Program – her contributions were invaluable. I know I can trust the integrity of everything she offers, and highly recommend scheduling a consult with Dr. Speer if anyone has concerns about potential medication interactions.

Erica Messinger | DNPc, BSN, RN, PMHNP
Psychiatric Mental Health Nurse Practitioner Candidate, Rural Health Nurse, Hospice Spiritual Care Counselor in Colorado
⭐⭐⭐⭐⭐

I worked with Dr. Speer on Colorado’s Natural Medicine screening criteria and trust her expertise completely. I’ve used her consultation services multiple times. They are excellent, professional and comprehensive. Our participants have directly benefited from her recommendations. I remember a particular case related to a GLP-1 med… Dr. Speer prevented the repeat of a problematic outcome using an approach we never would have thought of – and this is not taught in training programs. In addition to the initial pharmacological consult and review, she also offers a full comprehensive report that provides safety planning recommendations; a very helpful resource when needing to create safety plans for our clients that have received pharmacological conditional clearance from her. It is also helpful in structuring the conversation with clients about relevancy of next steps to promote the highest level of safety throughout their services. Dr. Speer has exceeded all expectations. She is my go-to and I encourage you to make her yours as well!

Mikki Vogt | MA, LPC, LAC, NMCF
Co-Founder & Clinical Director of The Center Origin, Denver, CO | Licensed Facilitator
⭐⭐⭐⭐⭐

Dr. Speer is great. I had NO issues with my last journey when we did what she recommended.

E.E. in unspecified US location
Participant
⭐⭐⭐⭐⭐

You get it. It’s not just about the medications, it’s about the whole person and their support system. I prefer to consult with you because you’re a true clinician.

T.D. in unspecified US location
Hospice & Palliative Physician
⭐⭐⭐⭐⭐

Dr. Speer’s comprehensive medication review gave me complete confidence in my psilocybin journey. Her personalized approach identified interactions I never would have considered and provided a clear preparation plan.

S.M. in unspecified US location
Personal use
⭐⭐⭐⭐⭐